马鸣, 教授, 博士生导师。2007年获新加坡国立大学博士学位。2008-2009年在耶鲁大学医学院肾内科从事博士后研究工作，2010-2017年被聘为副研究科学家。2017年入职西南大学。

马鸣实验室的主攻方向是“肾脏发育与肾脏遗传病研究”。其研究成果在以第一作者或者通讯作者发表在Nature Genetics (Article), Journal of the American Society of Nephrology, PLoS Genetics, Trends in Molecular Medicine, Cold Spring Harbor Perspectives in Biology, Seminars in Cell and Developmental Biology等杂志上。2013年美洲华人肾脏协会就其在肾脏病研究领域的贡献授予了奖状(Chinese American Society of Nephrology Outstanding Trainee Award)。2014年获得美国多囊肾病基金会的科研基金(PKD Foundation) Research Grant-In-Aid。2017年入选第13批“青年**”。现主持国家自然科学基金面上项目,国家重点研发计划子课题等项目。

实验室以小鼠，大鼠和斑马鱼为模型，研究方向为：

1.囊肿病的发病机理

2.纤毛在器官发育和稳态维持中的功能

3.肾脏上皮细胞分化

代表论文:

Lingfei Luo, Sudipto Roy, Li Li,Ming Ma. (2023). Polycystic kidney disease: novel insights into polycystin function. Trends in Molecular Medicine. 29(4):268-281 (Cover).

Fangying Zhao, Jiangyong He, Jun Tang, Nianfei Cui, Yanyan Shi, Zhifan Li, Shengnan Liu, Yazhou Wang, Ming Ma, Congjian Zhao, Lingfei Luo, Li Li. (2022). Brain milieu induces early microglial maturation through the BAX-Notch axis. Nature Communications. 13(1):6117.

Ke Dong, Chao Zhang, Xin Tian, Daniel Coman, Fhameed Hyder, Ming Ma, Stefan Somlo. (2021). Renal plasticity revealed through reversal of polycystic kidney disease in mice. Nature Genetics (Article). 53(12):1649-1663.

Zhaopeng Du, Xin Tian, Ming Ma, Stefan Somlo, Alan M Weinstein, Tong Wang. (2021). Restoration of proximal tubule flow-activated transport prevents cyst growth in polycystic kidney disease. JCI Insight. 24;6(10):e146041.

Ming Ma. (2021). Cilia and polycystic kidney disease. Seminars in Cell and Developmental Biology. 110:139-148.

Chao Zhang, Bruno Balbo, Ming Ma, Jun Zhao, Xin Tian, Yuval Kluger, Stefan Somlo. (2021). Cyclin-Dependent Kinase 1 Is a Driver of Cyst Growth in Polycystic Kidney Disease. Journal of the American Society of Nephrology. 32(1):41-51.

Ming Ma,Emilie Legué, Xin Tian, Stefan Somlo, Karel Jr. Liem. (2019). Cell-Autonomous Hedgehog Signaling Is Not Required for Cyst Formation in Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology. 30(11):2103-2111.

Youkui Huang, Yafang Lu, Yuepeng He, Zhi Feng, Yandong Zhan, Xue Huang, Qin Liu, Jingjing Zhang, Hongtao Li, Honghui Huang, Ming Ma, Lingfei Luo, Li Li (2019). Ikzf1 regulates embryonic T lymphopoiesis via Ccr9 and Irf4 in zebrafish. Journal of Biological Chemistry. 294(44):16152-16163.

Valeria Padovano, Ivana Y. Kuo, Lindsey K. Stavola, Hans R. Aerni, Benjamin J. Flaherty, Hannah C. Chapin, Ming Ma, Stefan Somlo, Alessandra Boletta, Barbara E. Ehrlich, Jesse Rinehart, and Michael J. Caplan. (2017). The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function. Molecular Biology of the Cell. 28(2):261-269.

Ming Ma,Anna-Rachel Gallagher, Stefan Somlo. (2017). Ciliary mechanisms of cyst formation in polycystic kidney disease. Cold Spring Harbor Perspectives in Biology. 9(11):a028209. (Cover).

Yuanyuan Li, Xin Tian, Ming Ma, Shanshan Kong, Stefan Somlo, Zhaoxia Sun (2016). Deletion of the Joubert syndrome gene Arl13b leads to cystic kidney in mouse. Journal of the American Society of Nephrology. 27(12): 3628-3638.

Ming Ma,Xin Tian, Peter Igarashi, Gregory J. Pazour, and Stefan Somlo (2013). Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease. Nature Genetics. (Article) 45(9):1004-1012.

Highlighted by Ellen F. Carney “Polycystic kidney disease: Cyst growth and cilia in ADPKD” in Nature Review Nephrology. 9, 555 (2013).

Highlighted by Ong A and Streets A: F1000 Prime Recommendation of [Ma M et al., Nat Genet 2013]. In F1000Prime, 30 Sep 2013.

Highlighted by Patankar JV. Novel cilia-dependent pathway activates rapid cyst growth in autosomal dominant polycystic kidney disease. Clinical Genet. 2014 Mar; 85 (3):230-2.

Hong Ma, Akashi Togawa, Keita Soda, Junhui Zhang, Sik Lee, Ming Ma, Zhiheng Yu, Thomas Ardito, Jan Czyzyk, Lonnette Diggs, Dominique Joly, Shinji Hatakeyama, Eiji Kawahara, Lawrence Holzman, Jun Lin Guan and Shuta Ishibe (2010). Inhibition of podocyte FAK protects against proteinuria and foot process effacement. Journal of the American Society of Nephrology. 21(7):1145-1156

Chung-Der Hsiao, May-Su You, Ying-Jey Guh, Ming Ma, Yun-Jin Jiang, Pung-Pung Hwang (2007). A Positive Regulatory Loop between foxi3a and foxi3b is Essential for Specification and Differentiation of Zebrafish Epidermal Ionocytes. PLoS ONE 2:e302

Ming Ma and Yun-Jin Jiang (2007). Jagged2a-Notch Signaling Mediates Cell Fate Choice in Zebrafish Pronephric Duct. PLoS Genetics. 3(1) e18. 8.

Ming Ma,Teck Koon TAN and Sek Man Wong (2003). Identification and molecular phylogeny of Epulorhiza isolates from tropical orchids. Mycological Research. 107: 1041-1049.

实验室招收对生物医学领域感兴趣的博士后和研究生。欢迎电邮联系，电子邮箱skymaming@swu.edu.cn